魏军统 助理教授

信息来源:bat365官网登录入口 发布时间:2023-11-09 11:31:18

  魏军统,青岛大学青年卓越人才,助理教授,硕士生导师。硕士毕业于清华大学化学系,博士毕业于香港浸会大学环境与生物分析国家重点实验室。研究领域为环境污染物暴露与人体健康,擅长基于液质联用的多组学分析。主持国家自然科学基金青年基金一项,省市级项目四项。发表SCI学术论文17篇,其中一作/共同一作8篇。授权国家发明专利一项。

一、主要研究方向

1、基于质谱的多组学技术在环境污染物的毒理方面的研究;

2、环境污染物的暴露分析、人群队列研究。

二、代表性科研成果

[1] J.T. Wei*, X.Y. Liu*, W.M. Xiao*, L. Guan, Z.F. Fang, J.P. Chen, B.Q. Sun, Z.W. Cai, X.Z. Sun, N.S. Zhong, Z.G. Liu, J. Yang#, X.J. Xiao#, S.K. Huang#, Phospholipid remodeling and its derivatives are associated with the severity of COVID-19, The Journal of Allergy and Clinical Immunology,2023,151(5),1259-1268.

[2]J.T. Wei*, X.J. Xiao*, K. Li, Y.Y. Song, S.K. Huang, Z.W. Cai#, Z.G. Liu#, Derivatization strategy for semi-quantitative analysis of medium- and long-chain fatty acids using multiple reaction monitoring, Talanta, 2021, 233,122464.

[3] J.T. Wei*, L. Xiang*, Z.W. Cai#, Emerging persistent organic pollutants hydroxylated polybrominated diphenyl ethers: from analytical methods to toxicology, Mass spectrometry reviews,2020, 00,1-25.

[4] J.T. Wei, X.N. Li, L. Xiang, Y.Y. Song, Y.C. Liu, Y.Y. Jiang, Z.W. Cai#, Metabolomics and lipidomics study unveils the impact of polybrominated diphenyl ether-47 on breast cancer mice,Journal of hazardous materials, 2019,390: 121451.

[5] J.T. Wei, L. Xiang, X.N. Li, Y.Y. Song, C.X. Yang, F.F. Ji, A.C. Chung, K. Li, Z.A. Lin, Z.W. Cai#,Derivatization strategy combined with parallel reaction monitoring for the characterization of short-chain fatty acids and their hydroxylated derivatives in mouse, Analytica Chimica Acta, 2020,1100:66-74.

[6] F.F. Ji*, J.T. Wei*, H.M. Luan, M. Li, Z.W. Cai#, Study of metabolic disorders associated with BDE-47 exposure in Drosophila model by MS-based metabolomics, Ecotoxicology and Environmental Safety, 184 (2019) 109606.

[7] J.T. Wei, L. Xiang, Z.G. Yuan, S.F. Li, C.X. Yang, H.X. Liu, Y.Y. Jiang, Z.W. Cai#, Metabolic profiling on the effect of 2,2 ',4,4 '-tetrabromodiphenyl ether (BDE-47) in MCF-7 cells, Chemosphere, 192 (2018) 297-304.

[8] J.T. Wei*, F. Jin*, Q. Wu, Y.Y. Jiang, D. Gao, H.X. Liu#, Molecular interaction study of flavonoid derivative 3d with human serum albumin using multispectroscopic and molecular modeling approach, Talanta, 126 (2014) 116-121. )

[9] 蔡宗苇,魏军统,王献,张海龙. 一种衍生化试剂及其制备方法与应用.中国,申请号:201810789929.5,2018.07.18

[10] L. Xiang, J.T. Wei, X.Y. Tian, B. Wang, W. Chan, S.F. Li, Z. Tang, H.S. Zhang, W.S. Cheang, Q. Zhao, H.Z. Zhao, Z.Y. Yang, Y.J. Hong, Y. Huang, Z.W. Cai, Comprehensive analysis of acylcarnitine species in db/db mouse using a novel method of high-resolution parallel reaction monitoring reveals widespread metabolic dysfunction induced by diabetes, Analytical chemistry, 89 (2017) 10368-10375.

[11] H.Z. Zhao, J.T. Wei, L. Xiang, Z.W. Cai, Mass spectrometry investigation of DNA adduct formation from bisphenol A quinone metabolite and MCF-7 cell DNA, Talanta, 182 (2018) 583-589.

[12] L. Xiang, H.S. Zhang, J.T. Wei, X.Y. Tian, H.M. Luan, S.F. Li, H.Z. Zhao, G.D. Cao, A.C.K. Chung, C.X. Yang, Y. Huang, Z.W. Cai, Metabolomics studies on db/db diabetic mice in skeletal muscle reveal effective clearance of overloaded intermediates by exercise, Analytica chimica acta, 1037 (2018) 130-139.

[13] C.X. Yang, C.M. Wong, J.T. Wei, A.C.K. Chung, Z.W. Cai, The brominated flame retardant BDE 47 upregulates purine metabolism and mitochondrial respiration to promote adipocyte differentiation, Science of the Total Environment, 644 (2018) 1312-1322.

[14] Q. Wu, D. Gao, J.T. Wei, F. Jin, W.Y. Xie, Y.Y. Jiang, H.X. Liu, Development of a novel multi-layer microfluidic device towards characterization of drug metabolism and cytotoxicity for drug screening, Chemical Communications, 50 (2014) 2762-2764.

[15] X. Gao, X. Bi, J.T. Wei, Z.M. Peng, H.X. Liu, Y.Y. Jiang, W. Wei, Z.W. Cai, N-phosphorylation labeling for analysis of twenty natural amino acids and small peptides by using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry, Analyst, 138 (2013) 2632-2639.

[16] Y.Y. Song, R.J. Li, Y.H. Zhang, J.T. Wei, W. Chen, C.K.A. Chung, Z.W. Cai, Mass spectrometry-based metabolomics reveals the mechanism of ambient fine particulate matter and its components on energy metabolic reprogramming in BEAS-2B cells, Science of the Total Environment, 651 (2019) 3139-3150.

[17] Q. Wu, J. Fang, S.F. Li, J.T. Wei, Z.Y. Yang, H.Z. Zhao, C. Zhao, Z.W. Cai, Interaction of bisphenol A 3,4-quinone metabolite with glutathione and ribonucleosides/deoxyribonucleosides in vitro, Journal of hazardous materials, 323 (2017) 195-202.

三、主要科研项目

1、国家自然科学基金青年科学基金项目:基于脂质组学对双酚S经芳香烃受体诱发加重过敏性哮喘分子机制的研究,资助金额:30万,研究期限:2022-01-01 至 2024-12-31,参与类型:主持。

2、中国博士后科学基金面上资助:双酚S诱发气道上皮细胞脂质代谢失衡加重哮喘的机制研究,资助金额:8万,参与类型:主持。

3、广东省自然科学基金项目:广东省基础与应用基础研究基金区域联合基金-青年基金项目,基于代谢组学双酚S对哮喘叠加作用及分子机制的研究,资助金额:10万,研究期限:2020-01-01至2022-12-31,参与类型:主持。

4、呼吸疾病国家重点实验室2022年度自主课题资助项目,基于质谱的多组学技术探究双酚S加重过敏性哮喘的分子机制,资助金额:20万,研究期限:2022-01-01 至 2024-12-31,参与类型:主持。

5、深圳市基础研究专项(自然科学基金)基础研究面上项目,环境挥发性有机物通过AhR-S1P轴引发哮喘的作用机制研究,资助金额:15万,2022-07-01-2025-06-30,参与类型:主持。

四、联系方式

E-mail: weijuntong2007@163.com


上一条:田舒菡 助理教授
下一条:魏潇然 助理教授

关闭